If you’ve been living with Dry Eye Disease (DED) symptoms, such as itching, burning, redness, irritation, grittiness, soreness of eyes, eyelid edema, foreign body sensation, watering, or blurred vision, it could be Meibomian Gland Dysfunction or MGD. Find out if participating in our research study could be a good option for you!

About the Study

The goal of the study is to evaluate the effectiveness and side effects of a potential new treatment option, AZR-MD-001 (an ointment applied to the lower eyelid), applied twice weekly for 12 months, compared to a *placebo, in volunteers with abnormal meibomian gland function and associated symptoms of Dry Eye Disease (DED).

Approximately 500 volunteers with Dry Eye Disease (DED) symptoms and evident Meibomian Gland Dysfunction (MGD) will be recruited across the United States. You may not realize you have MGD and the study team and physician will evaluate your eyes through a variety of assessments to determine if you do. If so, you may be eligible to participate!

The study will last about 13 months and includes up to nine in-clinic visits. Eligible participants may receive up to $2,000 in compensation for completing nine study visits. Reimbursement for transportation by car service (i.e., Uber, Lyft, Taxi) may be available.

To determine your eligibility, please complete the form below. Our patient recruitment team will contact you to ask more questions and provide more information about the study.

(A *placebo is a substance or treatment without real medical effects and is often used in studies to compare against the real treatment.)

You may also give us a call at 866-208-2583 or email us at recruitment@oraclinical.com.

DID YOU KNOW? Meibomian glands are the glands that line the edge of your eyelids, near your eyelashes that secrete the oil to coat the eyes and tear film, preventing the tears from evaporating too quickly.

Who Can Participate

You may qualify to participate if you:

Are 18 years or older

Are experiencing symptoms of Dry Eye Disease (DED) in both eyes for at least 3 months

Have evidence of Meibomian Gland Dysfunction (MGD) confirmed by the study team

Are willing to discontinue the use of:

  • All Dry eye treatments (prescribed or over-the-counter drops, ointments, or other).
  • All contact use (glasses only up to 13.5 months)
  • All eye makeup for the duration of your study participation (up to 13.5 months)

What Can You Expect

If you qualify for this study, here is what you can expect:

  • Study Visits: You will be asked to attend nine (9) in-clinic visits over approximately 13 months.
  • Compensation: For your time and participation and for completing 9 study visits, you may be compensated up to

During these visits, you will go through a series of assessments, including: 

  • Eye Exam: You will receive a comprehensive eye examination to assess your eye health.
  • Medical History: We will ask for your medical history and current medications, vitamins, and other supplements that you take. You will also be asked questions about your overall health, past diseases, and surgeries.  
  • Questionnaires: You will be asked to complete various study questionnaires to provide valuable information. 

In addition, there are other assessments that the study team will discuss with you in detail during your screening visit. 

Study Locations

We are currently conducting this study nationwide, with new locations coming soon. Take a look at our current locations below to find out if we have a study location near you. 

  • Apex, NC
  • Columbus, IN
  • Cranberry Twp, PA
  • Garner, NC
  • Glendale, CA
  • Goodlettsville, TN
  • Louisville, KY
  • Lynchburg, VA
  • Memphis, TN
  • Newport Beach, CA
  • Shelby, NC
  • Smyrna, TN
  • Sun City, AZ

Frequently Asked Questions

The study will last approximately 13 months and involves up to 9 in-person visits.

Taking part in any clinical study is entirely voluntary. Your decision whether or not to participate will not affect the medical care you currently receive or may receive in the future. If you qualify and opt to join the study, you have the freedom to withdraw at any time and for any reason.

Study medication and all study-related testing will be provided to you by the sponsor (Azura) at no
charge; however, taking part in this study may lead to added costs to you and/or your insurance company.
Tests and procedures that are routine care for your eye condition (not part of this research study) will be billed
to your insurance.

Your personal and medical information is completely protected before, during and after the clinical trial process through the HIPAA (Health Insurance Portability and Accountability Act) Privacy Rule. You will also be informed of who has access to your personal information.

Azura Ophthalmics is responsible for conducting this clinical study.

Visit our educational page to learn more about dry eye disease (DED).

General study information

A few questions to see if this study is right for you

Key requirements

Key Inclusion Criteria

Key Exclusion Criteria

Email moving fast icon

Receive Trial Alerts

Sign up for email alerts when new trials and locations are added for a medical condition.