Ocular discomfort is one of the primary symptoms of Dry Eye Disease (DED). Don’t just live with it! Join a research study evaluating a new investigational eye drop treatment.

About the Study

The goal of the study is to evaluate the effectiveness and side effects of a potential new treatment option compared to a *placebo, in volunteers with moderate to severe dry eye disease. (A *placebo is a substance or treatment without real medical effects and is often used in studies to compare against the real treatment.)

Approximately 400 volunteers with a history of ocular discomfort associated with Dry Eye Disease (DED) will be recruited across the United States.

The study will last about 8 weeks and includes up to 8 in-clinic visits. Eligible participants may receive up to $800 in compensation for completing all study visits.

To determine your eligibility, please complete the form below. Our patient engagement team will contact you to ask more questions and provide more information about the study.

You may also give us a call at 866-207-5695 or email us at recruitment@oraclinical.com

Dry Eye Disease (DED) is one of the most common reasons patients seek help from their eye doctor. By volunteering for research, help us make a difference in the lives of millions of people.

Who Can Participate

You may qualify to participate if you:

Are 18 years or older

Have been experiencing ocular discomfort associated with Dry Eye Disease (DED) for at least 6 months

Have used or desired to use eye drops for dry eye symptoms in the last 6 months

Have NOT had LASIK surgery in the last 12 months or any other eye surgery in the last 6 months

What Can You Expect

If you qualify for this study, here is what you can expect:

  • Study Visits: You will be asked to attend 8 in-clinic visits over approximately 8 weeks.
  • Compensation: For your time and participation you will be compensated $800.

During these visits, you will go through a series of assessments, including: 

  • Eye Exam: You will receive comprehensive eye exams to assess your eye health.  
  • Medical History: We will ask for your medical history and current medications, vitamins, and other supplements that you take. You will also be asked questions about your overall health, past diseases, and surgeries.  
  • Questionnaires: You will be asked to complete various study questionnaires to provide valuable information. 

In addition, there are other assessments that the study team will discuss with you in detail during your visits. 

Study Locations

We are currently conducting this study nationwide, with new locations coming soon. Take a look at our current locations below to find out if we have a study location near you. 

  • Charlotte, NC
  • Colorado Springs, CO
  • Garner, NC
  • Lynchburg, VA
  • Memphis, TN
  • Phoenix, AZ
  • Raynham, MA
  • Shelby, NC
  • Smyrna, TN
  • Sunrise, FL

Frequently Asked Questions

The study will last approximately 8 weeks and involves up to 8 inperson visits.

Taking part in any clinical study is entirely voluntary. Your decision whether or not to participate will not affect the medical care you currently receive or may receive in the future. If you qualify and opt to join the study, you have the freedom to withdraw at any time and for any reason.

Your personal and medical information is completely protected before, during and after the clinical trial process through the HIPAA (Health Insurance Portability and Accountability Act) Privacy Rule. You will also be informed of who has access to your personal information.

Aldeyra Therapeutics, Inc. is responsible for conducting this clinical study.

Visit our educational page to learn more about dry eye disease (DED).

General study information

A few questions to see if this study is right for you

Key requirements

Key Inclusion Criteria

Key Exclusion Criteria

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